Biomechanical Modeling of Posture and Movement Coordination: Fatigue, Gender and Aging effects

重复的运动通常是在日常生活活动中完成的，可能会导致疲劳。疲劳对个体肌肉和关节的影响已经被很好地记录下来；我们是第一批描述重复运动引起的疲劳的全身后果的人之一，揭示了利用肌肉骨骼系统的冗余的策略。我们发现，健康的疲劳适应与高度的运动变异性以及随着疲劳的发展而招募更多的关节和肌肉来完成任务有关。这些适应与跨越感觉、本体感觉和运动系统的变化有关。然而，性别和年龄等个人因素对工作相关疲劳适应能力的影响还不是很清楚，这限制了力学模型在准确表达正常健康疲劳适应模式范围方面的有效性。最近的统计数据显示，女性报告与工作有关的颈部/肩部MSD的比率较高。我之前已经发表了一个基于感觉运动控制基本知识的理论模型来解释这种观察；然而，这个模型的许多元素还没有确定。此外，加拿大人口预期寿命的持续增长、加拿大劳动力的老龄化和退休年龄的提高，使我们有必要了解老龄化如何影响一个人的适应疲劳的能力，无论是男性还是女性。这项研究计划的总体长期目标是更好地了解健康人上肢重复运动的生物力学和控制方面。现在将通过以下具体目标来解决这个问题：1)测量性别/性别对重复的上肢运动诱导的疲劳反应的肌肉、全身和感觉运动方面的影响；2)测量健康老龄化对重复的上肢运动诱导的疲劳反应的肌肉、全身和感觉运动方面的影响；3)确定性别/性别和年龄对重复上肢运动诱发疲劳反应的任务特异性的影响。将招募两个健康受试者(两个性别平衡组：一个年轻人(20-29岁)和一个老年人(54-65岁))执行低精度上肢任务和/或高精度上肢任务直到疲劳。我们将记录受试者在进行疲劳任务时的颈/肩感觉以及全身的运动学、运动学和肌肉活动特征。最近开发的变异性和肌肉间分析技术将用于描述与疲劳相关的运动策略。结果将有助于更好地理解和模拟性别/性别和年龄对疲劳反应的影响。这方面的知识可纳入机械模型和工作场所伤害预防办法。

Repetitive motions are often accomplished during activities of daily living and can lead to fatigue. The effects of fatigue on individual muscles and joints have been well documented; we were among the firsts to describe the whole-body consequences of repetitive motion-induced fatigue, uncovering strategies that take advantage of the musculoskeletal system's redundancy. We showed that healthy fatigue adaptations were associated with high movement variability and the recruitment of additional joints and muscles to contribute to the task as fatigue develops. These adaptations have been related to changes spanning the sensory, proprioceptive and motor systems. However, the effects of personal factors such as gender and aging on the ability to adapt to work-related fatigue is not well known, limiting the validity of mechanical models in accurately conveying the range of normal healthy fatigue adaptations patterns. Recent statistics show that women display a higher rate of reporting work-related neck/shoulder MSD. I have previously published a theoretical model based on fundamental knowledge of sensorimotor control to explain this observation; however, many elements of this model have not been identified yet. Moreover, the consistently increasing life expectancy of the Canadian population, the aging of the Canadian workforce and the increasing retirement age make it important for us to understand how aging affects one's ability to adapt to fatigue, in both men and women. The general, long-term objective of this research program is to gain a better understanding of the biomechanics and control aspects of upper limb repetitive movements in healthy humans. This will now be addressed using the following specific objectives: 1) Measure the effects of sex/gender on muscle, whole body and sensorimotor aspects of the repetitive upper limb motion-induced fatigue response; 2) Measure the effects of healthy aging on muscle, whole body and sensorimotor aspects of the repetitive upper limb motion-induced fatigue response; 3) determine the task-specificity of sex/gender and aging influences on the repetitive upper limb motion-induced fatigue response. Healthy subjects (two gender-balanced groups: one of young adults (20-29 years old), one of older adults (54-65 years old)) will be recruited to perform a low precision upper limb task and-or a high precision upper limb task until fatigue. We will record the neck/shoulder sensory, as well as the whole-body kinematic, kinetic and muscle activity characteristics as subjects perform the task to fatigue. Recently developed variability and between-muscle analysis techniques will be used to profile the fatigue-associated motor strategies. Results will help better understand and model the the effects of sex/gender and aging on the fatigue response. This knowledge could be integrated into mechanical models and into workplace injury prevention approaches.