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Investigations into sensing and metabolism of host lipids as a critical mediator of Staphylococcus aureus colonization and virulence

Investigations into sensing and metabolism of host lipids as a critical mediator of Staphylococcus aureus colonization and virulence
作为金黄色葡萄球菌定植和毒力关键介质的宿主脂质的传感和代谢研究
批准号：
445429
负责人：
Mcgavin Martin J
金额：
$44.03万
依托单位：
University of Western Ontario
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
未结题
起止时间：
2021-04-01 至 2026-04-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=445429&lang=en
关键词：
Acidic Ph Antimicrobial Fatty Acid Colonization Environmental Stress Gene Expression Innate Immunity Lipid Metabolism Staphylococcus Aureus Two Component Sensor System Virulence

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Approximately 30% of humans carry Staphylococcus aureus in their nose and on their skin. Although this represents an asymptomatic carrier state, S. aureus is also a leading cause of human infectious morbidity and mortality, and infections are caused by th
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