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Interactions between hippocampal vesicular acetylcholine transporter (VAChT) loss and amyloid pathology in circuit and cognitive deficits in Alzheimer's disease

Interactions between hippocampal vesicular acetylcholine transporter (VAChT) loss and amyloid pathology in circuit and cognitive deficits in Alzheimer's disease
海马囊泡乙酰胆碱转运蛋白(VAChT)丢失与阿尔茨海默病回路中淀粉样蛋白病理和认知缺陷之间的相互作用
批准号:
455703
负责人:
Prado Marco A
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-09-01 至 2022-09-01

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中文摘要
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英文摘要
Alzheimer's disease is thought to be caused by abnormal accumulation of amyloid beta proteins in the brain, which lead to neurodegeneration and dementia. However, most people over the age of 70 have amyloid in their brains, but the majority do not develop
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Canada Research Chair - Tier 1
  • 批准号:
    404350
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2018
  • 负责人:
    Prado Marco A
  • 依托单位:
Regulation of chaperone-mediated proteostasis by STI1
  • 批准号:
    388306
  • 项目类别:
    Operating Grants
  • 资助金额:
    $69.38万
  • 财政年份:
    2018
  • 负责人:
    Prado Marco A
  • 依托单位:
Regulation of neuronal resilience in Alzheimer's disease by the STI1/Prion protein complex
  • 批准号:
    304393
  • 项目类别:
    Operating Grants
  • 资助金额:
    $65.32万
  • 财政年份:
    2014
  • 负责人:
    Prado Marco A
  • 依托单位:
Novel mechanisms regulating functional recovery in stroke
  • 批准号:
    265869
  • 项目类别:
    Operating Grants
  • 资助金额:
    $51.84万
  • 财政年份:
    2012
  • 负责人:
    Prado Marco A
  • 依托单位:
海外基金