Self reactivity as a driver of extranodal diffuse large B-cell lymphoma transformation and progression.

自身反应性是结外弥漫性大 B 细胞淋巴瘤转化和进展的驱动因素。

• 批准号: 451542
• 负责人: Venturutti Leandro
• 金额: $ 83.04万
• 依托单位: BC Cancer, part of PHSA (Vancouver)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-09-01 至 2026-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=451542&lang=en
• 关键词: Autochthonous Mouse Models; B-Cell Lymphoma; Biomarkers; Extranodal Disease; Immune Niche; Malignant Transformation; Novel Therapeutics; Self-Reactivity; Signaling Cascades; Toll-Like Receptors

Lymphoma is a form of cancer that affects immune cells called lymphocytes, a type of white blood cell. There are many subtypes and maturation stages of lymphocytes and, therefore, many kinds of lymphomas. Diffuse large B-cell lymphomas (DLBCL), the most c

淋巴瘤是一种影响免疫细胞的癌症，称为淋巴细胞，一种白色血细胞。淋巴细胞有许多亚型和成熟阶段，因此有许多种淋巴瘤。弥漫性大B细胞淋巴瘤（DLBCL），