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Understanding the GR/PLZF axis in acute myeloid leukemia

Understanding the GR/PLZF axis in acute myeloid leukemia
了解急性髓系白血病的 GR/PLZF 轴
批准号:
452398
负责人:
Sauvageau Guy
金额:
$66.18万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01

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英文摘要
Mutations in the RUNX1 gene are involved in many diseases of the blood system. In acute myeloid leukemia (AML), the presence of RUNX1 mutations is associated with decreased survival. RUNX1 mutations are also observed in leukemia arising from hematological
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KBTBD4 determines key epigenetic marks that govern human hematopoietic stem cell self-renewal
  • 批准号:
    443734
  • 项目类别:
    Operating Grants
  • 资助金额:
    $75.24万
  • 财政年份:
    2021
  • 负责人:
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  • 依托单位:
Chemical and Genetic Interrogation of Human HSC Self-Renewal: Towards Optimal Cord Blood Grafts
BMI1 as a mutlifunctional protein master regulator of stem cell activity
  • 批准号:
    224393
  • 项目类别:
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  • 资助金额:
    $58.32万
  • 财政年份:
    2011
  • 负责人:
    Sauvageau Guy
  • 依托单位:
Identification of novel pathways essential for blood cell formation
  • 批准号:
    225540
  • 项目类别:
    Operating Grants
  • 资助金额:
    $49.35万
  • 财政年份:
    2011
  • 负责人:
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  • 依托单位:
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