课题基金 / 基金详情

Structure-guided in vitro and in situ analysis of virulence linked secretion systems in drug-resistant bacteria

Structure-guided in vitro and in situ analysis of virulence linked secretion systems in drug-resistant bacteria
耐药细菌毒力相关分泌系统的结构引导体外和原位分析
批准号:
452796
负责人:
Strynadka Natalie C
金额:
$90.56万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01

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中文摘要
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英文摘要
Bacteria have evolved sophisticated assemblies to passage macromolecules essential to subsequent disease across their lipid membrane barriers. The Type III Secretion system "injectisome" is one prominent example, a syringe like complex that is essential
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Reinforcing the battle at the bacterial cell wall: Structure-guided characterization and inhibition of beta-lactam antibiotic resistance signalling mechanisms
  • 批准号:
    480022
  • 项目类别:
    Operating Grants
  • 资助金额:
    $90.56万
  • 财政年份:
    2023
  • 负责人:
    Strynadka Natalie C
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COVID-19 Variant Supplement - Bespoke transition state analog inhibitors of SARS-CoV-2 3CL and PL proteases
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    443277
  • 项目类别:
    Operating Grants
  • 资助金额:
    $3.64万
  • 财政年份:
    2021
  • 负责人:
    Strynadka Natalie C
  • 依托单位:
COVID-19 Variant Network - Bespoke transition state analog inhibitors of SARS-CoV-2 3CL and PL proteases
  • 批准号:
    443340
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2021
  • 负责人:
    Strynadka Natalie C
  • 依托单位:
Bespoke transition state analog inhibitors of SARS-CoV-2 3CL and PL proteases
  • 批准号:
    429694
  • 项目类别:
    Operating Grants
  • 资助金额:
    $29.36万
  • 财政年份:
    2020
  • 负责人:
    Strynadka Natalie C
  • 依托单位: