Extrasynaptic NMDA receptors and resilience to chronic stress

突触外 NMDA 受体和慢性应激恢复能力

• 批准号: 456536
• 负责人: Wong Tak Pan
• 金额: $ 7.29万
• 依托单位: CIUSSS de l'Ouest-de-l'Ile-de-Montral-Douglas Hospital
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-09-01 至 2022-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=456536&lang=en
• 关键词: Calcium Imaging; Chronic Social Defeat Stress; Depression; Electrophysiology; Glutamate; Hippocampus; Longitudinal Studies; Nanoparticle; Phosphorylation; Social Memory

Depression is a stress-related mood disorder that affects 300 million people worldwide. Considering that up to 30% of depressed patients are resistant to current treatments, the development of more effective antidepressants is warranted. N-methyl-D-aspart

抑郁症是一种与压力有关的情绪障碍，影响着全球3亿人。考虑到高达30%的抑郁症患者对目前的治疗有抵抗力，开发更有效的抗抑郁药是必要的。N-甲基-D-门冬胰岛素