Uncovering the potential of therapeutic osteoclastogenesis in calcific cardiovascular disease through characterization of EV-mediated macrophage-smooth muscle cell communication

通过 EV 介导的巨噬细胞-平滑肌细胞通讯的表征，揭示破骨细胞生成在钙化性心血管疾病中的治疗潜力

• 批准号: 453913
• 负责人: Turner Mandy E
• 金额: $ 10.2万
• 依托单位: The Brigham and Women's Hospital, Inc. (Boston)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-09-01 至 2023-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=453913&lang=en
• 关键词: Extracellular Vesicles; Vascular Calcification

Millions of Canadians are affected by disease of the blood vessels whereby blood vessels accumulate crystals and calcify. These calcified vessels cause heart disease and have been linked to increased cardiovascular disease and deaths, however there are cu

数以百万计的加拿大人受到血管疾病的影响，血管积聚晶体和钙化。这些钙化的血管会导致心脏病，并与心血管疾病和死亡的增加有关，然而，