Physiology and cholinergic modulation of the medial prefrontal cortex - medial thalamus loop in female Rett Syndrome model mice

雌性雷特综合征模型小鼠内侧前额皮质 - 内侧丘脑环的生理学和胆碱能调节

• 批准号: 451188
• 负责人: Delaney Kerry R
• 金额: $ 56.29万
• 依托单位: University of Victoria (British Columbia)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-09-01 至 2026-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=451188&lang=en
• 关键词: Adeno-Associated Virus; Channel Rhodopsin; Cortex; Nicotinic Receptors; Rett Syndrome; Thalamus

Rett syndrome is a neurological disorder caused by mutations in a gene called MECP2 that controls many other genes to regulate the formation and function of brain circuits. Female patients get one X from their father, one from their mother but genes from

Rett综合征是一种神经系统疾病，由一种名为MECP 2的基因突变引起，该基因控制许多其他基因来调节大脑回路的形成和功能。女性患者从父亲那里得到一个X，从母亲那里得到一个，但基因来自