Investigation of Hepatitis B Virus Immunopathogenesis using Intravital Microscopy in the Woodchuck Hepatitis Virus (WHV) Model of Hepatitis B

使用活体显微镜在乙型肝炎土拨鼠肝炎病毒 (WHV) 模型中研究乙型肝炎病毒免疫发病机制

• 批准号: 450767
• 负责人: Coffin Carla S
• 金额: $ 64.93万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-09-01 至 2026-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=450767&lang=en
• 关键词: Acute And Chronic Hepatitis; Cytokines And Immune Cells; Hepatitis B Virus; Immunohistochemistry And Histology; Immunomodulatory Therapy; Intravital Microscopy; Liver Cancer And Liver Disease; Nucleos(T)Ide Analog Therapy; Peripheral Blood Mononuclear Cel

The hepatitis B virus (HBV) is a major cause of severe liver disease worldwide, including cirrhosis and liver cancer. There are drugs that can control the virus but they do not cure chronic infection. There is a need for greater understanding of the immun

B型肝炎病毒（HBV）是世界范围内严重肝病的主要原因，包括肝硬化和肝癌。有一些药物可以控制病毒，但它们不能治愈慢性感染。有必要对免疫系统有更深入的了解。