Striking a balance: mapping the structural stability and mechanical and chemical responsiveness of collagen proteins
Striking a balance: mapping the structural stability and mechanical and chemical responsiveness of collagen proteins
批准号:
RGPIN-2020-04680
负责人:
Forde, Nancy
金额:
$3.64万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-01-01 至 2021-12-31
中文摘要
多细胞生命是由一些结构构成的,这些结构将细胞维持在所需的位置和组织中。传统上,这些支架被认为是刚性的,在发育过程中铺设的不变的支撑,除非受伤或疾病,否则不会改变。最近的科学进展表明,这些细胞外支架是高度动态的,对其局部微环境的变化做出反应,并将这些变化传达给它们所支持的细胞,而这些细胞反过来又修改这些支架以适应变化的环境。
英文摘要
Multicellular life is scaffolded by structures that maintain cells in the desired locations and organizations. Conventionally these scaffolds are viewed as rigid, unchanging supports laid down during development and unaltered except by injury or disease. Recent scientific advances are revealing instead that these extracellular scaffolds are highly dynamic, responsive to changes in their local microenvironment and communicating these changes to the cells they support, which in turn modify these scaffolds to adapt to their changed environment.
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Striking a balance: mapping the structural stability and mechanical and chemical responsiveness of collagen proteins
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批准号:RGPIN-2020-04680
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项目类别:Discovery Grants Program - Individual
-
资助金额:$3.64万
-
财政年份:2022
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负责人:Forde, Nancy
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依托单位:
Striking a balance: mapping the structural stability and mechanical and chemical responsiveness of collagen proteins
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批准号:RGPAS-2020-00057
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项目类别:Discovery Grants Program - Accelerator Supplements
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资助金额:$2.91万
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财政年份:2022
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负责人:Forde, Nancy
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依托单位:
Striking a balance: mapping the structural stability and mechanical and chemical responsiveness of collagen proteins
-
批准号:RGPIN-2020-04680
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.64万
-
财政年份:2021
-
负责人:Forde, Nancy
-
依托单位:
Striking a balance: mapping the structural stability and mechanical and chemical responsiveness of collagen proteins
-
批准号:RGPAS-2020-00057
-
项目类别:Discovery Grants Program - Accelerator Supplements
-
资助金额:$2.91万
-
财政年份:2021
-
负责人:Forde, Nancy
-
依托单位:
Striking a balance: mapping the structural stability and mechanical and chemical responsiveness of collagen proteins
-
批准号:RGPAS-2020-00057
-
项目类别:Discovery Grants Program - Accelerator Supplements
-
资助金额:$2.91万
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财政年份:2020
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负责人:Forde, Nancy
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依托单位:
Interactive materials: guiding rational design through biomolecular characterization
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批准号:RGPIN-2015-05545
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2019
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负责人:Forde, Nancy
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依托单位:
Interactive materials: guiding rational design through biomolecular characterization
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批准号:RGPIN-2015-05545
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2018
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负责人:Forde, Nancy
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依托单位:
Interactive materials: guiding rational design through biomolecular characterization
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批准号:RGPIN-2015-05545
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2017
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负责人:Forde, Nancy
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依托单位:
Interactive materials: guiding rational design through biomolecular characterization
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批准号:RGPIN-2015-05545
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
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财政年份:2016
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负责人:Forde, Nancy
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依托单位:
Interactive materials: guiding rational design through biomolecular characterization
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批准号:RGPIN-2015-05545
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.5万
-
财政年份:2015
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负责人:Forde, Nancy
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依托单位:
Developing a molecular blueprint for mechanical response
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批准号:312576-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.57万
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财政年份:2014
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负责人:Forde, Nancy
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依托单位:
Developing a molecular blueprint for mechanical response
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批准号:312576-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.57万
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财政年份:2013
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负责人:Forde, Nancy
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依托单位:
Keratin mechanical characterization for the development of targeted hair care formulations
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批准号:461937-2013
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项目类别:Engage Grants Program
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资助金额:$1.82万
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财政年份:2013
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负责人:Forde, Nancy
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依托单位:
Developing a molecular blueprint for mechanical response
-
批准号:312576-2010
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项目类别:Discovery Grants Program - Individual
-
资助金额:$3.57万
-
财政年份:2012
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负责人:Forde, Nancy
-
依托单位:
Developing a molecular blueprint for mechanical response
-
批准号:312576-2010
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.57万
-
财政年份:2011
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负责人:Forde, Nancy
-
依托单位:
Developing a molecular blueprint for mechanical response
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批准号:312576-2010
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项目类别:Discovery Grants Program - Individual
-
资助金额:$3.57万
-
财政年份:2010
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负责人:Forde, Nancy
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依托单位:
Developing a molecular blueprint fo mechanical response
-
批准号:312576-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.7万
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财政年份:2009
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负责人:Forde, Nancy
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依托单位:
Developing a molecular blueprint fo mechanical response
-
批准号:312576-2008
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项目类别:Discovery Grants Program - Individual
-
资助金额:$2.7万
-
财政年份:2008
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负责人:Forde, Nancy
-
依托单位:
Developing a molecular blueprint fo mechanical response
-
批准号:312576-2005
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项目类别:Discovery Grants Program - Individual
-
资助金额:$2.7万
-
财政年份:2007
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负责人:Forde, Nancy
-
依托单位:
Developing a molecular blueprint fo mechanical response
-
批准号:312576-2005
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.7万
-
财政年份:2006
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负责人:Forde, Nancy
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依托单位:
国内基金
海外基金
双硫仑结合并抑制谷氨酸脱氢酶1活性调节Th17/Treg细胞平衡的作用与机制探究
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批准号:82371755
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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负责人:王秦兰
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依托单位: