Uncovering metabolic vulnerabilities of central nervous system leukemia using metabolic profiling of cerebrospinal fluid and an in vivo CRISPR screen
Uncovering metabolic vulnerabilities of central nervous system leukemia using metabolic profiling of cerebrospinal fluid and an in vivo CRISPR screen
批准号:
457141
负责人:
Wong Alan Y
金额:
$7.65万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-10-01 至 2024-10-01
中文摘要
白血病是加拿大最常见的儿童癌症,也是导致儿童癌症死亡的第二大原因。针对中枢神经系统(CNS)的化疗是治疗的关键部分,因为在那里扩散的白血病通常是失败的
英文摘要
Leukemia is the most common childhood cancer and the second greatest cause of pediatric cancer mortality in Canada. Chemotherapy directed to the central nervous system (CNS) is a critical part of treatment because leukemia that spreads there is often fata
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