Developmental Control of Chromatin Topology by Nuclear Mechanotransduction

通过核力转导控制染色质拓扑结构

• 批准号: 457553
• 负责人: Kim Yun-Kyo
• 金额: $ 10.93万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-11-01 至 2024-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=457553&lang=en
• 关键词: Chromatin Topology; Hox Cluster; Limb Development; Morphogenesis; Nuclear Mechanotransduction

The growth of an organ requires production of the correct shape with the correct identity of cells. When the embryo develops, it accomplishes both processes in a remarkably synchronized fashion. How this synchrony occurs is largely an open question. In ou

器官的生长需要产生具有正确形状和正确身份的细胞。当胚胎发育时，它以非常同步的方式完成这两个过程。这种同步如何发生在很大程度上是一个悬而未决的问题。在欧