Identifying novel adaptors and localization mechanisms of the neurological disease-associated protein, VPS13

识别神经疾病相关蛋白 VPS13 的新型接头和定位机制

• 批准号: 458989
• 负责人: Jeffers Kevin R
• 金额: $ 7.65万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-11-01 至 2024-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=458989&lang=en
• 关键词: Cellular Biology; Co-Immunoprecipitation; Fluorescent Microscopy; Genetics; Lipid Trafficking; Molecular Biology; Neurological Diseases; Protein Interactions; Vacuolar Protein Sorting; Yeast

In Canada, more than 1 in 500 people are affected by Parkinson's and similar movement disorders, such as ataxia. Mutations in the four human versions of vacuolar protein sorting 13 (VPS13) cause distinct neurological disorders, including these movement di

在加拿大，每500人中就有超过1人患有帕金森氏症和类似的运动障碍，如共济失调。液泡蛋白分选13 （VPS13）的四种人类版本的突变导致不同的神经系统疾病，包括这些运动障碍