Unveiling the Unique Transcriptomic Landscape of Ependymal Cells in Multiple Sclerosis and Neurodegeneration: A Multimodal Study of Cerebrospinal Fluid Dynamics and Periventricular Inflammation

揭示多发性硬化症和神经变性中室管膜细胞独特的转录组景观：脑脊液动力学和脑室周围炎症的多模式研究

• 批准号: 457467
• 负责人: Groh Adam M
• 金额: $ 10.93万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-11-01 至 2024-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=457467&lang=en
• 关键词: Animal Model; Cerebral Ventricle; Cerebrospinal Fluid; Ependymal Cell; Hydrocephalus; Magnetic Resonance Imaging; Multiple Sclerosis; Neuroimmunology; Neuroinflammation; Single Nuclear Transcriptomics

The brain is a complex organ composed of two primary cell types: neurons and glia. Neurons communicate through interfaces called synapses, which allow us to think, feel, and act. Glia are the true workhorses of the brain that support neurons in a variety

大脑是一个复杂的器官，由两种主要的细胞类型组成：神经元和胶质细胞。神经元通过称为突触的接口进行交流，突触允许我们思考、感觉和行动。神经胶质细胞是大脑中真正的主力，它支持各种神经元