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Large-scale study of patient-specific phenotypical, functional and proteomic differences in induced pluripotent stem cell-derived cardiomyocytes after hypoxic injury

Large-scale study of patient-specific phenotypical, functional and proteomic differences in induced pluripotent stem cell-derived cardiomyocytes after hypoxic injury
缺氧损伤后诱导多能干细胞来源的心肌细胞的患者特异性表型、功能和蛋白质组差异的大规模研究
批准号：
458860
负责人：
Derish Ida
金额：
$7.65万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-11-01 至 2024-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=458860&lang=en
关键词：
Cardiac Differentiation Cardiomyopathies Heart Failure Hypoxia Induced Pluripotent Stem Cells Patient-Specific Differences Proteomics Recovery

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中文摘要
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英文摘要
Heart attacks remain a leading cause of death worldwide and a major burden on the healthcare system, despite recent advances in medicine. During a heart attack, damage to heart cells can occur from a stop of blood flow and a subsequent oxygen restriction,
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会议论文
Decoding Dilated Cardiomyopathy in vitro: Linking Genetic Mutations to Phenotypic Dysfunction
  • 批准号：
    495567
  • 项目类别：
    Miscellaneous Programs
  • 资助金额：
    $0.44万
  • 财政年份：
    2023
  • 负责人：
    Derish Ida
  • 依托单位：
    University of Oxford (England)
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