Evaluation of the cholinergic effect of induced pluripotent stem cell (iPSC) derived parasympathetic neurons as an adjunct in alleviating xerostomia in Sjogren's syndrome.

评估诱导多能干细胞 (iPSC) 衍生的副交感神经元作为缓解干燥综合征口干症辅助手段的胆碱能作用。

• 批准号: 458820
• 负责人: Iyer Janaki S
• 金额: $ 7.65万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-11-01 至 2024-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=458820&lang=en
• 关键词: Induced Pluripotent Stem Cell; Salivary Gland Regeneration; Sjogren'S Syndrome; Stem Cell Therapy; Xerostomia

Sjogren's syndrome (SS) is a longstanding, progressive disease that is predominant in women and primarily involves decreased bodily fluid secretions. Lack of saliva and its associated symptoms, such as dry mouth, impaired speech, tooth decay, loss of tast

干燥综合征(SS)是一种长期的进行性疾病，以女性为主，主要表现为体液分泌减少。唾液缺乏及其相关症状，如口干、言语障碍、龋齿、味觉减退