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Investigating the role of oncogenic histone H3.3K27M mutations in pediatric diffuse intrinsic pontine glioma

Investigating the role of oncogenic histone H3.3K27M mutations in pediatric diffuse intrinsic pontine glioma
研究致癌组蛋白 H3.3K27M 突变在儿童弥漫性脑桥胶质瘤中的作用
批准号：
458960
负责人：
Lubanszky Evan
金额：
$7.65万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-11-01 至 2024-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=458960&lang=en
关键词：
Diffuse Intrinsic Pontine Glioma Diffuse Midline Glioma - H3k27m Mutant Epigenetics H3k27m Mutant Oncohistones Pediatric High Grade Glioma Synthetic Lethality Transgenic Mouse Modeling

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中文摘要
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英文摘要
Diffuse Intrinsic Pontine Glioma (DIPG) is a devastating disease that is the leading cause of brain-tumour related death in children, for which there is no effective treatment. There are many factors that contribute to this lack of treatments, including t
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Investigating the role of oncogenic H3.3K27M mutations in pediatric diffuse intrinsic pontine glioma
  • 批准号：
    428970
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2019
  • 负责人：
    Lubanszky Evan
  • 依托单位：
    University of Toronto