Investigating the Roles of Mitophagy and the Integrated Stress Response (ISR) in Intestinal Stem Cells

研究线粒体自噬和综合应激反应 (ISR) 在肠干细胞中的作用

• 批准号: 466794
• 负责人: Niu Keyu (Corie)
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-12-01 至 2022-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466794&lang=en
• 关键词: Colorectal Cancer; Immunology; Infectious Disease; Integrated Stress Response; Intestinal Disease; Intestinal Stem Cell Differentiation; Medicine; Mitochondrial Stress; Mitophagy; Tumorigenesis

The mitochondria is responsible for food metabolism and energy production inside the human body. In response to diverse mitochondrial stressors, eukaryotic cells initiate two distinct pathways, mitophagy and the integrated stress response (ISR), to reesta

线粒体负责人体内的食物代谢和能量产生。真核细胞对不同的线粒体应激源作出反应时，启动两种不同的途径，线粒体自噬和整合应激反应（ISR），