Elucidating the catalytic mechanism of the human Dicer enzyme using MD and QM/MM free energy techniques
Elucidating the catalytic mechanism of the human Dicer enzyme using MD and QM/MM free energy techniques
批准号:
558732-2021
负责人:
Nikkel, Dylan
金额:
$2.55万
依托单位:
依托单位国家:
加拿大
项目类别:
Alexander Graham Bell Canada Graduate Scholarships - Doctoral
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-01-01 至 2022-12-31
中文摘要
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英文摘要
Enzyme Mechanisms, Computational Chemistry, Human Enzymes, Dicer, DICER1 Syndrome, Cancer, RNase III, Molecular Dynamics, QM/MM Free Energy Methods, Thermodynamic Integration
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会议论文
A computational investigation into the mechanism of the human Dicer enzyme and known cancer causing variants
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批准号:553304-2020
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项目类别:Alexander Graham Bell Canada Graduate Scholarships - Master's
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资助金额:$1.27万
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财政年份:2020
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负责人:Nikkel, Dylan
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依托单位:
Multiscale Modeling of the MutY DNA Repair Enzyme
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批准号:541528-2019
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项目类别:University Undergraduate Student Research Awards
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资助金额:$0.33万
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财政年份:2019
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负责人:Nikkel, Dylan
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依托单位:
Computer Modeling of the Replication of Damaged DNA
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批准号:527201-2018
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项目类别:University Undergraduate Student Research Awards
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资助金额:$0.33万
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财政年份:2018
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负责人:Nikkel, Dylan
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依托单位:
Contribution of cottonwood trees to net methane exchange in riparian forests
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批准号:509512-2017
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项目类别:University Undergraduate Student Research Awards
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资助金额:$0.33万
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财政年份:2017
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负责人:Nikkel, Dylan
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依托单位:
国内基金
海外基金
二氧化碳与高碳烷烃耦合转化多相催化体系研究
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批准号:22372180
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项目类别:面上项目
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资助金额:50.00万元
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批准年份:2023
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负责人:崔新江
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依托单位:
复相催化“均相化”催化剂的制备及其性能研究
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批准号:20573095
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项目类别:面上项目
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资助金额:8.0万元
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批准年份:2005
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负责人:陈平
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依托单位: