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Improving early cancer diagnosis with Nanopore sequencing of cell-free DNA

Improving early cancer diagnosis with Nanopore sequencing of cell-free DNA
利用游离 DNA 的纳米孔测序改善早期癌症诊断
批准号：
467214
负责人：
Broadbent Jonathan P
金额：
$1.27万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-12-01 至 2022-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=467214&lang=en
关键词：
Bioinformatics Cell-Free Dna Early Cancer Diagnosis Fragmentation Liquid Biopsy Methylation Nanopore Sequencing Pan-Genomics Population Mapping Reference Graph Alignment

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Cancer mortality rates can be greatly ameliorated by improving early diagnosis mechanisms and routinely screening the population. However, most tumour diagnosis methods are highly invasive and unfeasible for mass screening. The possibility of screening fo
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