The role of ketones on the maturation of energy metabolism in the cardiomyocyte

酮对心肌细胞能量代谢成熟的作用

• 批准号: 466753
• 负责人: Persad Kaya L
• 金额: $ 1.27万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-12-01 至 2022-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466753&lang=en
• 关键词: Beta-Hydroxybutyrate; Cardiomyocyte; Differentiation; Fatty Acid Oxidation; Glucose Oxidation; Glycolysis; Ketone Oxidation; Maturation; Metabolism; Warburg Effect

Approximately 40,000 babies born each year are born with problems regarding the structure/function of their heart (congenital heart defects- CHD), with 1in 4 babies having critical CHD. 4.2% of all newborn deaths are due to CHD, with 48% of death due to C

每年约有40,000名新生儿出生时心脏结构/功能有问题(先天性心脏病)，每4名婴儿中就有1名患有严重的心脏病。4.2%的新生儿死亡是由于冠心病，其中48%的死亡是由丙型肝炎引起的。