Investigating the molecular mechanisms of a novel group of small-molecule Bax inhibitors

研究一组新型小分子 Bax 抑制剂的分子机制

• 批准号: 466493
• 负责人: Aljghami Mazen E
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-12-01 至 2022-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466493&lang=en
• 关键词: Apoptosis Prevention; Bcl-2 Protein Dynamics; Drug Development; Drug-Protein Interactions; Mitochondrial Dynamics; Molecular Mechanisms; Prevention Of Neuronal Degeneration (E.G.In Stroke; Protein-Protein Interactions; Reducing Chemotherapy Cytotoxic Side

The mitochondria has always been known as the ;powerhouse of the cell. However, the association between neuronal health and mitochondrial function is something that is not widely known. When a neuronal cell encounters a stressor during a stroke (oxygen de

线粒体一直被认为是细胞的发电站。然而，神经元健康和线粒体功能之间的关联并不广为人知。当神经元细胞在中风期间遇到应激源时（氧气释放），