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Investigating the molecular mechanisms of a novel group of small-molecule Bax inhibitors

Investigating the molecular mechanisms of a novel group of small-molecule Bax inhibitors
研究一组新型小分子 Bax 抑制剂的分子机制
批准号：
466493
负责人：
Aljghami Mazen E
金额：
$1.27万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-12-01 至 2022-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466493&lang=en
关键词：
Apoptosis Prevention Bcl-2 Protein Dynamics Drug Development Drug-Protein Interactions Mitochondrial Dynamics Molecular Mechanisms Prevention Of Neuronal Degeneration (E.G.In Stroke Protein-Protein Interactions Reducing Chemotherapy Cytotoxic Side

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The mitochondria has always been known as the ;powerhouse of the cell. However, the association between neuronal health and mitochondrial function is something that is not widely known. When a neuronal cell encounters a stressor during a stroke (oxygen de
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