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Regulation of LRIG1 and its functional role following brain injury.

Regulation of LRIG1 and its functional role following brain injury.
脑损伤后 LRIG1 的调节及其功能作用。
批准号：
466731
负责人：
Ouzikov Stephanie
金额：
$1.27万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-12-01 至 2022-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466731&lang=en
关键词：
Brain Injury Cell Signalling Inhibition Cellular Differentiation Central Nervous System Gene Expression Gene Targeting Leucine-Rich Repeats And Immunoglobulin-Like Domains 1 Neural Stem Cells Neurogenesis Stroke

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Neural stem cells (NSCs) are largely quiescent in nature and divide infrequently for brain maintenance and during times of brain injury. However, even after stroke injury, these newborn neurons migrate to the lesion site, of which most NSC die. LRIG1 is a
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