Role of dendritic spines in the processing, storage, and integration of excitatory inputs in neocortical pyramidal neurons

树突棘在新皮质锥体神经元兴奋性输入的处理、存储和整合中的作用

• 批准号: 462423
• 负责人: Araya Roberto
• 金额: $ 78.58万
• 依托单位: Universit de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-03-01 至 2027-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=462423&lang=en
• 关键词: Dendritic Physiology; Dendritic Spines; Ion Channels; Neocortex; Non-Linear Microscopy; Pyramidal Neurons; Stdp; Synaptic Integration; Synaptic Transmission; Two-Photon Imaging/Uncaging

The fundamental operation of any neuron is to integrate synaptic inputs in order to decide when to fire an action potential. However, how neurons integrate thousands of inputs in order to make this decision is still unclear. Further, the presence of dendr

任何神经元的基本操作都是整合突触输入，以决定何时发射动作电位。但是，神经元如何整合成千上万的输入以做出此决定尚不清楚。此外，dendr的存在