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Hyperactive mitochondria: a novel mechanism to explain early life stress-related sleep apneas in adult mice

Hyperactive mitochondria: a novel mechanism to explain early life stress-related sleep apneas in adult mice
线粒体过度活跃：解释成年小鼠早期生活压力相关睡眠呼吸暂停的新机制
批准号：
461071
负责人：
Soliz Jorge
金额：
$51.27万
依托单位：
Institut universitaire de cardiologie et de pneumologie de Qubec - U Laval
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-03-01 至 2027-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=461071&lang=en
关键词：
Brainstem Breathing Dysfunction Gaba Hypothalamo-Pituitary-Adrenal Axis Mitochondria Neonatal Tress Nucleus Tractus Solitarii (Nts) Paraventricular Nucleus Of The Hypothalamus (Pvh) Sex Dimorphism Sleep Apnea

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Mitochondria are small organelles within cells that generate almost all the energy we need throughout life. The human brain, being the most energy-demanding organ, consumes between 50% (in postnatal age) and 20% (in adulthood) of this energy. In fact, the
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Targeting sex mitochondrial asymmetry to elucidate sex-specific consequences of intermittent hypoxia in newborns
  • 批准号：
    377722
  • 项目类别：
    Operating Grants
  • 资助金额：
    $10.93万
  • 财政年份：
    2017
  • 负责人：
    Soliz Jorge
  • 依托单位：
    Universit Laval
Cerebral erythropoietin as a novel mechanism to explain sex-specific respiratory depression in neonates