FOXM1 protein-targeted degradation and its potential role in the treatment of ovarian cancer: a medicinal chemistry approach

FOXM1 蛋白靶向降解及其在卵巢癌治疗中的潜在作用：一种药物化学方法

• 批准号: 463226
• 负责人: Velazquez Carlos A
• 金额: $ 53.22万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-03-01 至 2027-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=463226&lang=en
• 关键词: Drug Design; Forkhead Box Proteins; Foxm1; Medicinal Chemistry; Molecular Modeling; Ovarian Cancer; Transcription; Transcription Factors

The long-term goal of our research program is to understand the molecular recognition process that takes place between a special type of protein involved in cancer development and drug molecules. Specifically, we seek to establish the best way to develop

我们研究计划的长期目标是了解参与癌症发展的一种特殊类型的蛋白质和药物分子之间发生的分子识别过程。具体地说，我们寻求建立发展的最佳方式