Contribution of Predicted High-Impact Genetic Variants in Multi-system Inflammatory Syndrome in Children & Adolescents (MIS-C)

预测的高影响遗传变异对儿童多系统炎症综合征的贡献

• 批准号: 468243
• 负责人: Mendes de Aquino Marla
• 金额: $ 4.3万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-07-01 至 2023-07-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=468243&lang=en
• 关键词: Covid-19 As A Trigger For Mis-C; Damaging Variants; Genetic Architecture; Mis-C

Approximately four to six weeks after infection by SARS-CoV-2, some children (316 per 1000000) presented a multisystem inflammatory syndrome with features of Kawasaki disease. While the condition can be considered rare, it is very severe in clinical impac

在SARS-CoV-2感染后约4 - 6周，一些儿童（316/100万）出现了具有川崎特征的多系统炎症综合征。虽然这种情况可以被认为是罕见的，但在临床上是非常严重的。