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Contribution of Predicted High-Impact Genetic Variants in Multi-system Inflammatory Syndrome in Children & Adolescents (MIS-C)

Contribution of Predicted High-Impact Genetic Variants in Multi-system Inflammatory Syndrome in Children & Adolescents (MIS-C)
预测的高影响遗传变异对儿童多系统炎症综合征的贡献
批准号：
468243
负责人：
Mendes de Aquino Marla
金额：
$4.3万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2022
资助国家：
加拿大
项目状态：
已结题
起止时间：
2022-07-01 至 2023-07-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=468243&lang=en
关键词：
Covid-19 As A Trigger For Mis-C Damaging Variants Genetic Architecture Mis-C

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Approximately four to six weeks after infection by SARS-CoV-2, some children (316 per 1000000) presented a multisystem inflammatory syndrome with features of Kawasaki disease. While the condition can be considered rare, it is very severe in clinical impac
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