Sex differences in Neural and Molecular Mechanisms Underlying Negative Cognitive Bias

消极认知偏差背后的神经和分子机制的性别差异

• 批准号: 468102
• 负责人: Galea Liisa A
• 金额: $ 70.5万
• 依托单位: Centre for Addiction and Mental Health (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2027-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=468102&lang=en
• 关键词: Cognition; Cytokines; Depression; Hippocampus; Limbic System; Microglia; Neurogenesis; Neuroinflammation; Sex Differences; Stress

Major depressive disorder (MDD) affects 20% of the population and females are twice more likely to develop MDD compared with males. Furthermore, cognitive symptoms of depression, including negative cognitive bias, are more severe in females than in males.

重度抑郁症（MDD）影响了20%的人口，女性患重度抑郁症的可能性是男性的两倍。此外，抑郁症的认知症状，包括消极认知偏见，在女性中比在男性中更严重。