The role of ependymal cells in multiple sclerosis progression

室管膜细胞在多发性硬化症进展中的作用

• 批准号: 472974
• 负责人: Stratton Jo A
• 金额: $ 21.86万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2025-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=472974&lang=en
• 关键词: Ependymal Cells; Human Brain Parenchyma-Csf Barrier Cell Analysis; Immune-Epithilium Interactions; Neurodegeneration; Single Cell Transcriptomics; Transgenic Animal Models & Behaviour

Ependymal cells line the fluid filled spaces in the brain and function as key barrier cells between cerebral spinal fluid (CSF) and the underlying brain tissue. There primary function is to regulate CSF flow important for maintaining overall brain health.

室管膜细胞排列在脑内充满液体的空隙中，是脑脊液(CSF)和下层脑组织之间的关键屏障细胞。它们的主要功能是调节脑脊液流量，这对维持整体大脑健康非常重要。