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Defining thymic B cell origin and function

Defining thymic B cell origin and function
定义胸腺 B 细胞的起源和功能
批准号：
469740
负责人：
Lesage Sylvie
金额：
$67.71万
依托单位：
Centre de recherche de l'Hôpital Maisonneuve-Rosemont (Montral)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-09-01 至 2027-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=469740&lang=en
关键词：
Autoimmunity B Cells Cellular Immunology Central Tolerance Immune Tolerance Mouse Models T Cells Thymus

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英文摘要
Autoimmune diseases develop as a result of an aberrant immune response against self-tissues. In many of these diseases, T cells are the primary mediators of tissue damage. Elimination of pathogenic T cells during their development in the thymus is therefo
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