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Targeted and immuno-therapy to overcome innate and acquired resistance in aggressive MAPK-addicted cancers.

Targeted and immuno-therapy to overcome innate and acquired resistance in aggressive MAPK-addicted cancers.
靶向和免疫治疗可克服侵袭性 MAPK 成瘾癌症的先天性和获得性耐药性。
批准号：
469037
负责人：
Nichols Anthony C
金额：
$72.17万
依托单位：
University of Western Ontario
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-09-01 至 2027-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=469037&lang=en
关键词：
Anaplastic Thyroid Cancer Braf Mutation Immunotherapy Single Cell Sequencing Syngeneic Mouse Models Targeted Therapy Thyroid Cancer Whole Genome Sequecing

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Thyroid cancer is one of the fastest rising cancers in Canada. Most thyroid cancers are non-aggressive types and are almost always cured with surgery. In contrast, anaplastic thyroid cancer (ATC) accounts for only 1% of thyroid cancers but is perhaps the
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