Evolution of mosquito-virus interactions: range expansions, viral coinfections and mosquito behaviour
蚊子-病毒相互作用的演变:范围扩大、病毒共感染和蚊子行为
基本信息
- 批准号:RGPIN-2020-05200
- 负责人:
- 金额:$ 2.91万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2021
- 资助国家:加拿大
- 起止时间:2021-01-01 至 2022-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
There are three research foci in my lab. (1) TAXONOMY and SYSTEMATICS We will be studying the incursions of two mosquito species into Canada, namely Aedes albopictus (Asian Tiger mosquito) and Aedes aegypti (Yellow Fever mosquito), by tracing the phylogenetic relationships of established and novel populations using DNA sequences. We will also undertake a revision of 8 species in the mosquito genus Culiseta to determine how they are related to one another; such information is necessary for understanding the transmission of Eastern Equine Encephalitis virus. (2) BEHAVIOURAL ECOLOGY Earlier work on the effects of sugar-feeding among the blood-feeding Diptera has suggested that honeydew sugar meals offer enhanced flight capabilities and may protect mosquitoes from some protozoan infections. In contrast, nectar meals may offer enhanced vitellogenesis which presumably leads to increased egg production. We aim to examine the effects of honeydew vs. nectar meals on longevity and fecundity in mosquitoes. This will be followed by choice experiments in which we determine whether the gender, age, size, mating status and/or infection status of mosquitoes influences the type of sugar-meal ingested. (3) DISEASE TRANSMISSION In addition to ongoing vector competence studies to determine which mosquitoes are able to transmit which viruses, we are interested in the effects of dual infection with two strains of the same virus as well as with two different viruses. We intend to study Zika virus, Mayaro virus and eventually Dengue virus and Yellow Fever virus. Co-infection and superinfection studies will be done in cell culture first and then in live, infected mosquitoes in Brock's Containment Level 3 Lab with Insectary.
我的实验室有三个研究重点。 (1)分类学和昆虫学我们将研究两种蚊子入侵加拿大的情况,即白纹伊蚊(亚洲虎蚊)和埃及伊蚊(黄热病蚊),方法是利用DNA序列追踪已建立和新种群的系统发育关系。我们还将对库利塞蚊属的8种蚊子进行修订,以确定它们之间的关系;这些信息对于了解东方马脑炎病毒的传播是必要的。 (2)行为生态学早期关于吸血双翅目中糖喂食的影响的研究表明,蜜露糖餐提供了增强的飞行能力,并可能保护蚊子免受某些原生动物的感染。相比之下,花蜜餐可能会提供增强的卵黄发生,这可能会导致卵子产量增加。我们的目的是研究蜜露与花蜜对蚊子寿命和繁殖力的影响。随后将进行选择实验,确定蚊子的性别、年龄、大小、交配状态和/或感染状态是否会影响摄入的糖粉类型。 (3)疾病传播除了正在进行的媒介能力研究以确定哪些蚊子能够传播哪些病毒外,我们还对同一病毒的两种毒株以及两种不同病毒的双重感染的影响感兴趣。我们打算研究寨卡病毒、马亚罗病毒,最终研究登革热病毒和黄热病病毒。将首先在细胞培养物中进行共感染和重复感染研究,然后在Brock的3级昆虫实验室中进行活的受感染蚊子研究。
项目成果
期刊论文数量(0)
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Hunter, Fiona其他文献
BET 1: Intravenous tranexamic acid in the treatment of acute epistaxis.
- DOI:
10.1136/emermed-2015-204985.1 - 发表时间:
2015-12-01 - 期刊:
- 影响因子:0
- 作者:
Fox, Hannah;Hunter, Fiona - 通讯作者:
Hunter, Fiona
Hunter, Fiona的其他文献
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{{ truncateString('Hunter, Fiona', 18)}}的其他基金
Evolution of mosquito-virus interactions: range expansions, viral coinfections and mosquito behaviour
蚊子-病毒相互作用的演变:范围扩大、病毒共感染和蚊子行为
- 批准号:
RGPIN-2020-05200 - 财政年份:2022
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Evolution of mosquito-virus interactions: range expansions, viral coinfections and mosquito behaviour
蚊子-病毒相互作用的演变:范围扩大、病毒共感染和蚊子行为
- 批准号:
RGPIN-2020-05200 - 财政年份:2020
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Systematics, Behavioural Ecology and Disease Transmission of Biting Diptera
咬性双翅目的系统学、行为生态学和疾病传播
- 批准号:
RGPIN-2015-03802 - 财政年份:2019
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Systematics, Behavioural Ecology and Disease Transmission of Biting Diptera
咬性双翅目的系统学、行为生态学和疾病传播
- 批准号:
RGPIN-2015-03802 - 财政年份:2018
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Efficacy of Greenlid Biotraps towards arbovirus-infected mosquitoes**
Greenlid Biotrap 对虫媒病毒感染的蚊子的功效**
- 批准号:
536449-2018 - 财政年份:2018
- 资助金额:
$ 2.91万 - 项目类别:
Engage Grants Program
Systematics, Behavioural Ecology and Disease Transmission of Biting Diptera
咬性双翅目的系统学、行为生态学和疾病传播
- 批准号:
RGPIN-2015-03802 - 财政年份:2017
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Entomological risk assessment for BTV and EHDV affecting cattle in Ontario and Quebec
对影响安大略省和魁北克省牛的 BTV 和 EHDV 进行昆虫学风险评估
- 批准号:
501037-2016 - 财政年份:2016
- 资助金额:
$ 2.91万 - 项目类别:
Engage Grants Program
Systematics, Behavioural Ecology and Disease Transmission of Biting Diptera
咬性双翅目的系统学、行为生态学和疾病传播
- 批准号:
RGPIN-2015-03802 - 财政年份:2016
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Systematics, Behavioural Ecology and Disease Transmission of Biting Diptera
咬性双翅目的系统学、行为生态学和疾病传播
- 批准号:
RGPIN-2015-03802 - 财政年份:2015
- 资助金额:
$ 2.91万 - 项目类别:
Discovery Grants Program - Individual
Viral diagnostics in vector-borne mosquitoes from Guanacaste in Costa Rica
哥斯达黎加瓜纳卡斯特媒介传播蚊子的病毒诊断
- 批准号:
469431-2014 - 财政年份:2014
- 资助金额:
$ 2.91万 - 项目类别:
Engage Grants Program
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