The function and regulation of tissue resident alveolar macrophages turnover by host and environmental factors during homeostasis and in infections

稳态和感染期间宿主和环境因素对组织驻留肺泡巨噬细胞周转的功能和调节

• 批准号: 471247
• 负责人: Qin Wanhai
• 金额: $ 10.2万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2024-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=471247&lang=en
• 关键词: Alveolar Macrophage; Bacterial Pneumonia; Epigenetic Regulation; Influenza A Virus; Macrophage Turnover; Microbiome; Sars-Cov2; Trained Immunity

With 3 million deaths per year, lower respiratory tract infections are the leading infectious cause of death and the fifth-leading cause of death overall. Therefore, it is extremely important to understand how our respiratory immune system works and poten

下呼吸道感染每年造成300万人死亡，是导致死亡的主要传染性原因，也是总体死亡的第五大原因。因此，了解我们的呼吸道免疫系统如何工作并增强免疫力是非常重要的。