Small molecule inhibitor of IL-1b signaling in degenerative disc disease

椎间盘退行性变是一种进行性疾病，到70岁时会影响大约60%的人口，通常会导致虚弱的下腰痛。由于椎间盘修复不是自发发生的，因此经常需要手术干预来治疗腰椎间盘突出症。

Intervertebral disc degeneration is a progressive disorder that affects about 60% of the population by age 70, often resulting in debilitating low back pain. As disc repair does not occur spontaneously, surgical intervention is often needed for treating p