Understanding epigenetic regulation and modulation of cell stress responses by the cholesterol transporter, scavenger receptor-B1 as a novel target for treating advanced prostate cancer
Understanding epigenetic regulation and modulation of cell stress responses by the cholesterol transporter, scavenger receptor-B1 as a novel target for treating advanced prostate cancer
批准号:
469855
负责人:
Cox Michael E
金额:
$69.66万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-09-01 至 2027-09-01
中文摘要
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英文摘要
The male hormone, testosterone is the primary driver of prostate cancer (PCa). This androgen hormone sustains PCa growth and survival by activating the androgen receptor. Drugs called androgen receptor targeted agents (ARTAs) are the primary treatment for
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会议论文
Development of targeted therapeutics for ERG-expressing prostate cancers
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批准号:344451
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项目类别:Operating Grants
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资助金额:$29.24万
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财政年份:2016
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负责人:Cox Michael E
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依托单位:
ERG-induced transformation of prostatic epithelial cells
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批准号:183802
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2008
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负责人:Cox Michael E
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依托单位:
国内基金
海外基金
PDLIM3-Cholesterol-SMO轴调控SHH通路激活及其在髓母细胞瘤中的功能研究
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批准号:82072798
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项目类别:面上项目
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资助金额:55.0万元
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批准年份:2020
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负责人:张丽
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依托单位:
以促内涵体逃逸聚合物PEG-P[Asp(TEP)]-cholesterol为载体构建双级脑靶向基因传递系统沉默BACE1基因的研究
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批准号:81302714
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项目类别:青年科学基金项目
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资助金额:23.0万元
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批准年份:2013
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负责人:俞媛
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依托单位: