Homeostatic regulation failure in epilepsy renders cortical circuits less heterogeneous

癫痫的稳态调节失败导致皮质回路异质性降低

• 批准号: 473682
• 负责人: Rich Scott
• 金额: $ 6.56万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-10-01 至 2024-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=473682&lang=en
• 关键词: Applied Mathematics; Computational Neuroscience; Epilepsy; Mathematical Modeling; Neural Networks; Neuron Models; Neuronal Degeneracy; Neuronal Homeostasis; Rhythms And Oscillations; Seizure

Epilepsy is the most common serious neurological disorder in the world, affecting approximately a quarter of a million Canadians. However, around a third of patients with epilepsy do not see their seizure burden reduced by current pharmacological treatmen

癫痫是世界上最常见的严重神经疾病，影响着大约25万加拿大人。然而，大约三分之一的癫痫患者并没有看到目前的药物治疗减轻了他们的癫痫负担。