Development of a synthetic safety switch to control graft related arrhythmias following human stem cell-derived cardiomyocyte transplantation post-myocardial infarction

开发一种合成安全开关来控制心肌梗塞后人干细胞源性心肌细胞移植后移植物相关的心律失常

• 批准号: 476773
• 负责人: Alibhai Faisal J
• 金额: $ 3.28万
• 依托单位: University Health Network (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-10-01 至 2023-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=476773&lang=en
• 关键词: Cardiovascular Disease; Cell Transplanation; Electrophysiology; Myocardial Infarction; Stem Cells; Synthetic Biology

Each year 70,000 Canadians suffer a heart attack (myocardial infarction; MI), which contributes to the majority of the newly diagnosed cases of heart failure. Following a heart attack the heart cannot regenerate, and instead lost muscle is replaced with n

每年有70，000加拿大人遭受心脏病发作（心肌梗死; MI），这是大多数新诊断的心力衰竭病例的原因。心脏病发作后，心脏不能再生，而失去的肌肉会被新的蛋白质替代。