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Identifying essential genes for epithelial homeostasis and KRas-driven carcinomas using in vivo CRISPR screens.

Identifying essential genes for epithelial homeostasis and KRas-driven carcinomas using in vivo CRISPR screens.
使用体内 CRISPR 筛选鉴定上皮稳态和 KRas 驱动的癌症的必需基因。
批准号:
477267
负责人:
Schramek Daniel
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-10-01 至 2023-10-01

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英文摘要
Identifying and targeting genes that are essential for tumor cells lies at the heart of precision oncology. Typically, drug target discovery involves screening large chemical or pooled CRISPR libraries. However, the in vitro conditions and cancer cell lin
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Deciphering the molecular & cellular basis of Low-Grade Glioma
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    478958
  • 项目类别:
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  • 财政年份:
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