Limiting homocysteine toxicity to rescue brain development after methotrexate treatment in pediatric acute lymphoblastic leukemia

限制同型半胱氨酸毒性以挽救儿童急性淋巴细胞白血病甲氨蝶呤治疗后的大脑发育

• 批准号: 475505
• 负责人: Choi Sun Eui
• 金额: $ 7.65万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-11-01 至 2025-11-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=475505&lang=en
• 关键词: Cancer; Chemotherapy; Imaging; Neuroscience

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, affecting over 300 patients and families each year. Recent advances in treatment, led by new combination chemotherapy regimens, has meant over 90% of patients are cured of their disea

急性淋巴细胞白血病 (ALL) 是最常见的儿童癌症，每年影响 300 多名患者和家庭。以新的联合化疗方案为代表的最新治疗进展意味着超过 90% 的患者的疾病得到治愈