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Determining the long-term outcomes and optimal treatment of childhood nephrotic syndrome using population-based administrative health data, target trial emulation, and a pilot adaptive clinical trial of a precision medicine treatment strategy

Determining the long-term outcomes and optimal treatment of childhood nephrotic syndrome using population-based administrative health data, target trial emulation, and a pilot adaptive clinical trial of a precision medicine treatment strategy
使用基于人群的管理健康数据、目标试验模拟和精准医学治疗策略的试点适应性临床试验来确定儿童肾病综合征的长期结果和最佳治疗
批准号：
475537
负责人：
Robinson Cal
金额：
$7.65万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-11-01 至 2025-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=475537&lang=en
关键词：
Adaptive Clinical Trial Administrative Healthcare Database Bayesian Pilot Study Prospective Cohort Study Target Trial Emulation

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中文摘要
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英文摘要
Nephrotic syndrome is one of the most common childhood kidney diseases. It affects up to 3,000 Canadian children each year. In nephrotic syndrome, the kidneys leak protein into the urine, which causes the body to swell. This causes breathing problems, inf
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Evaluating a precision medicine approach to nephrotic syndrome using novel genetic risk profiles: A pilot adaptive clinical trial
  • 批准号：
    466596
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2021
  • 负责人：
    Robinson Cal
  • 依托单位：
    University of Toronto