Investigation of chondroitin sulfate glycocalyx restructuring and function during prostate cancer progression

前列腺癌进展过程中硫酸软骨素糖萼的重组和功能研究

• 批准号: 476050
• 负责人: Tahiry Zakir
• 金额: $ 7.65万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-11-01 至 2025-11-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=476050&lang=en
• 关键词: Androgen Deprivation; Chondroitin Sulfate Glycosaminoglycans; Glycocalyx; Prostate Cancer; Prostate Cancer Metastases

Cancer cells are coated with chains of sugar molecules which are collectively called the glycocalyx. The glycocalyx plays an important role in cell-to-cell signaling and communication, and harbors growth factors to encourage cell survival and division. Ca

癌细胞被糖分子链包裹，这些糖分子统称为糖萼。糖萼在细胞间的信号传递和通讯中发挥重要作用，并含有促进细胞生存和分裂的生长因子。钙