Targeting metabolic reprogramming in SWI/SNF-mutant cancers

针对 SWI/SNF 突变癌症的代谢重编程

• 批准号: 486322
• 负责人: Ho Rebecca
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486322&lang=en
• 关键词: Gynecologic Cancer; Metabolic Shifts And Vulnerabilities; Mouse Xenograft Cancer Models; Swi/Snf Deficient Cancers; Tissue Microarray

Genes, short regions of DNA, contain the instructions for a cell to grow and do its job. Within a cell, large molecules called remodelling complexes turn genes on or off and limit what set of instructions the cell can access. This system separates the sha

基因是DNA的短区域，包含细胞生长和工作的指令。在细胞内，被称为重塑复合体的大分子开启或关闭基因，并限制细胞可以访问的指令集。这一制度将沙地分开。