The role of innate immunity in promoting microbiota-dependent mucus production in the proximal colon

先天免疫在促进近端结肠微生物依赖的粘液产生中的作用

• 批准号: 486486
• 负责人: Fancy Noah M
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486486&lang=en
• 关键词: Colitis/Inflammatory Bowel Disease; Colon; Ex Vivo; Germ Free/Gnotobiotic; Goblet Cell; Humanized Microbiota; In Vivo; Microbiota; Mucus; Pattern Recognition Receptors

Inflammatory Bowel Disease (IBD) is a chronic disorder of the gut in which the intestinal walls are bombarded by the immune system, leading to ulceration and diarrhea. The cause is unknown, but has been associated with the gut microbiota (all the microorg

炎症性肠病（IBD）是肠道的慢性疾病，其中肠壁被免疫系统轰炸，导致溃疡和腹泻。原因是未知的，但与肠道微生物群有关（所有Microg