Characterizing and navigating the landscape of genomic 'secondary findings' in pediatric cancer patients of diverse backgrounds

描述和探索不同背景的儿科癌症患者的基因组“二次发现”景观

• 批准号: 475504
• 负责人: Majeed Safa
• 金额: $ 7.65万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-11-01 至 2025-11-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=475504&lang=en
• 关键词: Bioinformatics; Cancer Disease Management; Germline Variants; Health Policy; Methodological Framework; Pediatric Oncology; Rna Sequencing; Secondary Findings; Whole Genome Sequencing

Over the last decade, genomic sequencing of childhood cancers has yielded dramatic insights into their molecular processes and underpinnings; however, the discovery of genetic mutations not known to be related to the biology of a patient's cancer remains

在过去的十年中，儿童癌症的基因组测序对其分子过程和基础产生了深刻的见解。然而，未知与患者癌症生物学相关的基因突变的发现仍然存在