Effect of TRPML1 inhibition by Helicobacter pylori vacuolating cytotoxin on mitochondrial dynamics and function

幽门螺杆菌空泡细胞毒素抑制 TRPML1 对线粒体动力学和功能的影响

• 批准号: 485981
• 负责人: Novielli Julia
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=485981&lang=en
• 关键词: Bacterial Survival; Dynamin-Related Protein 1 (Drp1); Gastric Cancer; Helicobacter Pylori; Host-Pathogen Interactions; Mitochondrial Dynamics; Vacuolating Cytotoxin A (Vaca)

Helicobacter pylori is a bacterium that infects the stomachs of ~50% of the world’s population and is the most important cause of gastric cancer. Thus, there is an urgent need to understand how H. pylori causes disease and develop new strategies to treat

幽门螺杆菌是一种感染全球约 50% 人口胃部的细菌，是导致胃癌的最重要原因。因此，迫切需要了解幽门螺杆菌如何引起疾病并制定新的治疗策略