Mechanisms of ribosome dysfunction during aging

衰老过程中核糖体功能障碍的机制

• 批准号: 486519
• 负责人: Danielson Katie J
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486519&lang=en
• 关键词: Age-Associated Disease; Aging; Protein Homeostasis; Ribosome; Rna Structure; Translation

Aging is characterized by the progressive dysregulation and deterioration of biological processes over time. One of the most important biological processes is protein synthesis, and its role in protein homeostasis is critical to maintain functionality of

衰老的特征是随着时间的推移，生物过程逐渐失调和恶化。最重要的生物过程之一是蛋白质合成，并且其在蛋白质稳态中的作用对于维持细胞的功能性至关重要。