Targeting pro-inflammatory effector functions of islet macrophages using lipid nanoparticles to prevent diabetes

使用脂质纳米颗粒靶向胰岛巨噬细胞的促炎效应子功能来预防糖尿病

• 批准号: 486117
• 负责人: Ostromecki Courtney
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486117&lang=en
• 关键词: Autoimmune; Diabetes; Inflammation; Macrophages; Nanomedicine; Nod Mice; Pancreatic Beta Cell

Type 1 diabetes (T1D) is an autoimmune disease in which the immune system mistakenly attacks the insulin-producing beta cells of the pancreas. Macrcophages are a type of immune cell - the garbage eaters of the body - that can be found in the pancreas in c

1型糖尿病（T1 D）是一种自身免疫性疾病，其中免疫系统错误地攻击胰腺的胰岛素产生β细胞。巨噬细胞是一种免疫细胞--身体的垃圾进食者--可以在c.