Identifying driver genes in head and neck squamous cell carcinoma using an in vivo CRISPR-activation screen

使用体内 CRISPR 激活筛选鉴定头颈鳞状细胞癌的驱动基因

• 批准号: 485982
• 负责人: Nurtanto Jocelyn
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=485982&lang=en
• 关键词: Copy Number Alterations; Crispr-A; Hnscc; Screening; Tumorigenesis

Novel sequencing technologies have been revolutionary in uncovering genetic alterations within deadly head and neck cancers. However, despite this intricate knowledge of sequence alterations in these tumours, we still do not know what causes the cancer to

新的测序技术在发现致命的头颈癌中的基因变化方面具有革命性。然而，尽管对这些肿瘤的序列改变有如此复杂的了解，我们仍然不知道是什么原因导致癌症