The Transcription Factor Autoimmune Regulator (AIRE) Acts as a Vitamin D Receptor Coactivator
The Transcription Factor Autoimmune Regulator (AIRE) Acts as a Vitamin D Receptor Coactivator
批准号:
486309
负责人:
Karabatsos Sophia
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-12-01 至 2023-12-01
中文摘要
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英文摘要
The autoimmune regulator AIRE regulates the transcription of tissue-restricted antigens (TRAs) within epithelial cells of the thymus. This allows elimination of any developing T lymphocytes that are reactive to self, thus preventing autoimmune responses.
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